Results: 2

1.
Figure 2

Figure 2. Survival analysis of MDS patients with DNMT3A mutations. From: Recurrent DNMT3A Mutations in Patients with Myelodysplastic Syndromes.

(A) the overall survival of MDS patients with DNMT3A mutations compared to MDS patients without DNMT3A mutations. (B) the event-free survival of MDS patients with or without DNMT3A mutations. (C) progression to AML in MDS patients with or without DNMT3A mutations.

Matthew J. Walter, et al. Leukemia. ;25(7):1153-1158.
2.
Figure 1

Figure 1. Location of mutations in the DNMT3A gene. From: Recurrent DNMT3A Mutations in Patients with Myelodysplastic Syndromes.

The positions and predicted translational consequences of DNMT3A mutations detected in 150 MDS samples are shown. Each circle is a mutation found in one patient. One patient has two mutations in DNMT3A. The conserved proline-tryptophan-tryptophan-proline (PWWP), zinc finger (ZNF), and methyltransferase (MTase) domains are shown.
*, stop codon.

Matthew J. Walter, et al. Leukemia. ;25(7):1153-1158.

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