Results: 4

1.
Figure 4

Figure 4. From: Early Determinants of Pulmonary Vascular Remodeling in Animal Models of Complex Congenital Heart Disease.

Relevance network of genes belonging to angiogenesis related signaling pathways identified using Pathway Architect software. Yellow indicates the genes that are altered between Shunt and Control lambs at 3-days of age.

Sohrab Fratz, et al. Circulation. ;123(8):10.1161/CIRCULATIONAHA.110.978528.
2.
Figure 3

Figure 3. From: Early Determinants of Pulmonary Vascular Remodeling in Animal Models of Complex Congenital Heart Disease.

The Carnitine Shuttle and role of carnitine in the mitochondrial oxidation of fatty acids. Abbreviations: CPT-I, carnitine palmitoyltransferase-1; CPT-II, carnitine palmitoyltransferase-2; CACT, carnitine acylcarnitine translocase; CrAT, carnitine acetyl transferase; OMM, outer mitochondrial membrane; IMM, inner mitochondrial membrane.

Sohrab Fratz, et al. Circulation. ;123(8):10.1161/CIRCULATIONAHA.110.978528.
3.
Figure 2

Figure 2. From: Early Determinants of Pulmonary Vascular Remodeling in Animal Models of Complex Congenital Heart Disease.

Representative H & E stains of peripheral lung fixed in 4% paraformaldehyde and sectioned at 7 microns, from 4-week control (left) and Shunt (right) lambs. Note the increase in medial thickness in the Shunt lambs. Magnification=20×.

Sohrab Fratz, et al. Circulation. ;123(8):10.1161/CIRCULATIONAHA.110.978528.
4.
Figure 1

Figure 1. From: Early Determinants of Pulmonary Vascular Remodeling in Animal Models of Complex Congenital Heart Disease.

Retrospective analysis of n= 69 consecutive patients younger than 15 months (subgroup of reference 9) with single ventricle physiology who underwent and survived partial cavo-pulmonary connection (PCPC). The X-axis depicts age at PCPC in months. The Y-axis depicts transpulmonary gradient defined as left atrial pressure minus pulmonary artery pressure during heart catheterization before total cavo-pulmonary connection (TCPC) surgery.

Sohrab Fratz, et al. Circulation. ;123(8):10.1161/CIRCULATIONAHA.110.978528.

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