Results: 3

1.
Figure 2

Figure 2. Hospital risk adjusted mortality with and without compassionate use variable. From: Improvement in Mortality Risk Prediction Following Percutaneous Coronary Intervention Through Addition of a "Compassionate Use" Variable to the National Cardiovascular Data Registry CathPCI(R) Dataset: A Study from the Massachusetts Angioplasty Registry.

Posterior mean risk-standardized mortality rates and corresponding 95% intervals (x-axis) for each MA hospital (y-axis) based on a hierarchical model excluding the compassionate use variable (solid line) and on a hierarchical model including the compassionate use variable (dashed line).

Frederic S. Resnic, et al. J Am Coll Cardiol. ;57(8):904-911.
2.
Figure 1

Figure 1. Impact of inclusion of compassionate use (CU) on predicted mortality. From: Improvement in Mortality Risk Prediction Following Percutaneous Coronary Intervention Through Addition of a "Compassionate Use" Variable to the National Cardiovascular Data Registry CathPCI(R) Dataset: A Study from the Massachusetts Angioplasty Registry.

Impact of inclusion of compassionate use (CU) indicator on predicted mortality for patients in the high risk (cardiogenic shock or STEMI) cohort. The horizontal axis represents the predicted mortality excluding CU, while the vertical axis represents predicted mortality after inclusion of the CU indicator covariate. The diagonal line indicates no change in predicted mortality for individual cases. The cases with CU features had significant increases in their predicted mortality, which further discriminated patients who survived versus those who suffered an in hospital fatality.

Frederic S. Resnic, et al. J Am Coll Cardiol. ;57(8):904-911.
3.
Figure 3

Figure 3. Emergent revascularization for cardiogenic shock in MA, 2003–2007. From: Improvement in Mortality Risk Prediction Following Percutaneous Coronary Intervention Through Addition of a "Compassionate Use" Variable to the National Cardiovascular Data Registry CathPCI(R) Dataset: A Study from the Massachusetts Angioplasty Registry.

Temporal trends of the prevalence of treatment for cardiogenic shock for both the PCI (maroon columns) and isolated CABG (blue columns) cohorts in MA, 2003–2007. The red arrow indicates the time of introduction of compassionate use indicator covariates in the PCI mortality prediction models. There was no change in the risk prediction methodology for isolated CABG during the study period. A change in the prevalence of cardiogenic shock as an indication for PCI is noted to be temporally associated with the introduction of the CU indicator covariate.

Frederic S. Resnic, et al. J Am Coll Cardiol. ;57(8):904-911.

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