Results: 5

1.
Fig. 1

Fig. 1. From: Targeted Multifunctional Multimodal Protein-Shell Microspheres as Cancer Imaging Contrast Agents.

Multimodal multifunctional protein-shell microspheres. a Sonication apparatus for the synthesis of protein microspheres. b Schematic representation, c TEM, and d SEM of protein microspheres.

Renu John, et al. Mol Imaging Biol. ;14(1):17-24.
2.
Fig. 2

Fig. 2. From: Targeted Multifunctional Multimodal Protein-Shell Microspheres as Cancer Imaging Contrast Agents.

a Coronal and b sagittal MRI slices of a control rat and a normal rat after injection with non-targeted iron oxide microspheres. The arrow-marked regions in the MRI, after injection of iron oxide protein microspheres, show strong negative T2 contrast due to the presence of iron oxide.

Renu John, et al. Mol Imaging Biol. ;14(1):17-24.
3.
Fig. 5

Fig. 5. From: Targeted Multifunctional Multimodal Protein-Shell Microspheres as Cancer Imaging Contrast Agents.

Multimodal imaging of multifunctional microspheres. a MM-OCT image showing both magnetomotive (green) and structural (red) signals from the tumor site. b High-magnification (63×) fluorescence microscopy of the tumor showing intact Nile red-containing microspheres (arrows) as well as evidence of microsphere rupture (diffuse red signal).

Renu John, et al. Mol Imaging Biol. ;14(1):17-24.
4.
Fig. 4

Fig. 4. From: Targeted Multifunctional Multimodal Protein-Shell Microspheres as Cancer Imaging Contrast Agents.

High-resolution real-time ultrasound imaging of tumor following injection of engineered protein microspheres. a Identified microspheres (green channel) within tumor, superimposed over grey-scale B-mode image. b Transient scattering changes (green trace) following bolus injection. c Transient scattering changes (green trace) following a sequence of rupture pulses (red regions), showing increases in scattering immediately after rupture pulses, followed by a gradual decrease in scattering, suggesting possible rupture of microspheres.

Renu John, et al. Mol Imaging Biol. ;14(1):17-24.
5.
Fig. 3

Fig. 3. From: Targeted Multifunctional Multimodal Protein-Shell Microspheres as Cancer Imaging Contrast Agents.

High-resolution real-time in vivo ultrasound images of rat mammary tumor and microbubble transients. a Tumor imaged with 15 MHz probe. b Doppler flow imaging identifying vascular region. c Transient increase in scattering (green trace) following commercial microbubble injection. d Rapid decrease in scattering (green trace) following delivery of rupture pulse (red region).

Renu John, et al. Mol Imaging Biol. ;14(1):17-24.

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