We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

Results: 3

1.
Figure 2

Figure 2. From: Automated hippocampal shape analysis predicts the onset of dementia in Mild Cognitive Impairment.

Hippocampal shape pattern discriminative between Alzheimer’s disease (AD) and healthy controls, which was also predictive of the risk of transition to AD in subjects with Mild Cognitive Impairment. Negative numbers represent atrophy in AD subjects. Figure in radiological convention (Left is Right).

Sergi G. Costafreda, et al. Neuroimage. ;56(1):212-219.
2.
Figure 3

Figure 3. From: Automated hippocampal shape analysis predicts the onset of dementia in Mild Cognitive Impairment.

Subjects with Mild Cognitive Impairment predicted to develop Alzheimer’s disease based on their hippocampal morphometry (N=33, dashed lines) show faster decline over the 12 month follow-up in both verbal memory (CERAD delayed memory scores, p<0.01) and general cognitive function (MMSE total score, p<0.01) than MCI subjects predicted to remain stable (N=70, solid lines).

Sergi G. Costafreda, et al. Neuroimage. ;56(1):212-219.
3.
Figure 1

Figure 1. From: Automated hippocampal shape analysis predicts the onset of dementia in Mild Cognitive Impairment.

Statistical significance maps for a) differences in atrophy between subjects with Mild Cognitive Impairment who developed Alzheimer’s disease (AD) within 12 months of follow-up (N=22) and those who did not (N=81); b) correlation in MCI subjects between atrophy and 12-month memory decline as measured by the CERAD delayed recall score (N=103) and c) correlation between atrophy and MMSE total score (N=103). The maps are adjusted for age, sex, baseline score (CERAD and MMSE) and intracranial volume. While the maps represent uncorrected p-values for local atrophy, a significant effect remained after multiple comparison correction at the set-level through permutation testing, except for the association between left hippocampal atrophy and MMSE score. Figures are in radiological convention (Left is Right).

Sergi G. Costafreda, et al. Neuroimage. ;56(1):212-219.

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Write to the Help Desk