Results: 3

1.
Figure 1

Figure 1. From: Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22.

Q-Q plot of the expected vs observed distribution of p-values.

Evangelos Evangelou, et al. Ann Rheum Dis. 2011 February;70(2):349-355.
2.
Figure 3

Figure 3. From: Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22.

a) Forest plot of study-specific estimates (black boxes) and summary OR estimates and 95% confidence intervals (95% CIs) (diamond) for the association between the rs4730250 SNP and knee osteoarthritis.

Evangelos Evangelou, et al. Ann Rheum Dis. 2011 February;70(2):349-355.
3.
Figure 2

Figure 2. From: Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22.

Regional association plot of rs4730250. Statistical significance of the associated SNPs are illustrated on –log10 scale. The p-value of the rs4730250 and the other 10 selected SNPs are based on the meta-analysis of all datasets (both GWA studies and replication studies). P-values for the rest of the SNPs are based on the meta-analysis of the GWA studies. The sentinel SNP is shown in blue. The correlation of the sentinel SNP is shown on a scale from minimal (gray) to maximal (red). SNPs in red have r2≥0.8 with the sentinel SNP and SNPs in orange have r2≥ 0.5. Chromosome positions are based on HapMap release 22 build 36.

Evangelos Evangelou, et al. Ann Rheum Dis. 2011 February;70(2):349-355.

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