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Results: 5

1.
Fig. 2.

Fig. 2. From: Regional correlation of emphysematous changes in lung function and structure: a comparison between pulmonary function testing and hyperpolarized MRI metrics.

Multislice maps of fractional ventilation (r, top) and ADC (bottom) in a representative elastase-treated rat lung. Pixels with r ≈ 1.0 and ADC ≥ 0.5 (cm2/s) are masked in the histograms. The mean ± SD of each slice is shown above each histogram for the respective truncated distribution.

Kiarash Emami, et al. J Appl Physiol (1985). 2011 January;110(1):225-235.
2.
Fig. 3.

Fig. 3. From: Regional correlation of emphysematous changes in lung function and structure: a comparison between pulmonary function testing and hyperpolarized MRI metrics.

Threshold curves and 80% r and ADC threshold values for all rats in both groups. A: r* denotes the threshold value in each animal above which 80% of lung voxels assume their r values. B: ADC* denotes the threshold value in each animal below which 80% of lung voxels assume their ADC values. The 80% threshold quantities (right) correspond to the intercept of the horizontal dashed line with the threshold curves (left).

Kiarash Emami, et al. J Appl Physiol (1985). 2011 January;110(1):225-235.
3.
Fig. 1.

Fig. 1. From: Regional correlation of emphysematous changes in lung function and structure: a comparison between pulmonary function testing and hyperpolarized MRI metrics.

Multislice maps of fractional ventilation (r, top) and apparent diffusion coefficient (ADC, bottom) in a representative healthy rat lung. Pixels with r ≈ 1.0 and ADC ≥ 0.5 (cm2/s) are masked in the histograms. The mean ± SD of each slice is shown above each histogram for the respective truncated distribution.

Kiarash Emami, et al. J Appl Physiol (1985). 2011 January;110(1):225-235.
4.
Fig. 5.

Fig. 5. From: Regional correlation of emphysematous changes in lung function and structure: a comparison between pulmonary function testing and hyperpolarized MRI metrics.

Regional ADC and r correlations shown for each of the 3 images slices in all rats. Each data point corresponds to 1 quadrant of the imaged slice in a given rat. Twelve data points from each rat are therefore plotted on the r-ADC sample space. The rigid line represents the best fit to each dataset with the correlation coefficient shown at top of each panel.

Kiarash Emami, et al. J Appl Physiol (1985). 2011 January;110(1):225-235.
5.
Fig. 4.

Fig. 4. From: Regional correlation of emphysematous changes in lung function and structure: a comparison between pulmonary function testing and hyperpolarized MRI metrics.

Correlation of global pulmonary parameters with relevant 80% r* (A, C, E) and ADC* threshold values (B, D, F). When possible the parameter space has been divided into 2 or 4 zones corresponding to a nonoverlapping set of parameters. Note that imaging parameters invariably allow for clustering the animals into 2 different zones. FEV50, forced expiratory volume in 50 ms; FRC, functional residual capacity; RI, airway resistance; Cdyn, dynamic compliance, TLC, total lung capacity.

Kiarash Emami, et al. J Appl Physiol (1985). 2011 January;110(1):225-235.

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