Results: 2

1.
Figure 2.

Figure 2. From: Chlorine Gas Inhalation.

Scheme of some of the reactions potentially causing formation of reactive oxygen and nitrogen species in the setting of acute chlorine inhalation.

Carl W. White, et al. Proc Am Thorac Soc. 2010 July 1;7(4):257-263.
2.
Figure 1.

Figure 1. From: Chlorine Gas Inhalation.

Postulated mechanisms for airways injury due to chlorine inhalation. Hydration of chlorine gas (Cl2) leads to formation of HCl and HOCl (hypochlorous acid). As indicated, both Cl2 and HOCl can react with airway lining constituents. Reactive oxygen species (ROS) such as superoxide (O2−.), hydrogen peroxide (H2O2), and potentially hydroxyl radical can be formed both via recruited neutrophils and via secondary mitochondrial dysfunction. Neutrophil myeloperoxidase may form additional HOCl from hydrogen peroxide. Induction of nitric oxide synthase (iNOS) can lead to formation of nitric oxide (·NO) and, secondarily, peroxynitrite (ONOO). All of these reactive species can contribute to further airways injury, edema, and inflammation, immediate airway constriction, and persistent airways reactivity.

Carl W. White, et al. Proc Am Thorac Soc. 2010 July 1;7(4):257-263.

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Write to the Help Desk