Results: 2

1.
Figure 2

Figure 2. From: PINCH-2 expression in cancers involving serosal effusions using quantitative PCR.

PINCH-2 protein expression in serous effusions. Quantitative flow cytometric analysis of PINCH-2 protein levels, representative example for each of the three specimen types and control cells. (a) Malignant mesothelioma effusion. The majority of tumour cells (92.1%) are co-labelled by the epithelial membrane antigen (EMA) and PINCH-2 antibodies. (b) Ovarian carcinoma effusion. Co-labelling of 15.1% of tumour cells by the Ber-EP4 epithelial marker and PINCH-2. (c) Breast carcinoma effusion. Co-labelling of 55.9% of tumour cells by the Ber-EP4 and PINCH-2 antibodies. (d) The ovarian carcinoma cell line (OVCAR-3) expresses PINCH-2 in 98.3% of cells.

Y. Yuan, et al. Cytopathology. ;22(1):22-29.
2.
Figure 1

Figure 1. From: PINCH-2 expression in cancers involving serosal effusions using quantitative PCR.

PINCH-2 mRNA expression in serous effusions. Quantitative PCR amplification plots for PINCH-2 mRNA in a representative series of 47 effusions (29 ovarian carcinomas, 9 malignant mesotheliomas, 9 breast carcinomas). Cases were run in triplicate. The cycle threshold value (curve crossing the red horizontal line) is clearly lower for MM compared with ovarian and breast carcinoma effusions, denoting higher mRNA expression in the former tumor. Final values were established as ratio to level of the reference gene GUS (see also text).

Y. Yuan, et al. Cytopathology. ;22(1):22-29.

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