Results: 2

1.
Figure 1.

Figure 1. From: Refining the association of MHC with multiple sclerosis in African Americans.

Linkage disequilibrium decay. LD (D′) was calculated pair-wise between SNPs within 300 kb of each other using 2822 common polymorphic SNPs for 42 individuals from each population. HapMap populations: ASW, African American; CEU, European; YRI, Yoruban; AAMS, African American individuals in the current study.

Joseph P. McElroy, et al. Hum Mol Genet. 2010 August 1;19(15):3080-3088.
2.
Figure 2.

Figure 2. From: Refining the association of MHC with multiple sclerosis in African Americans.

MHC-wide MS association analysis results in the discovery cohort. The first principal component, which was derived from principal component analysis of 4248 non-chromosome 6 SNPs and is highly correlated with percent European ancestry, was included as a covariate in the logistic regression models. Red and blue dots indicate the –log10 (P-value) for the genotypic and trend models, respectively. (A) No SNPs in the model. (B) Most significant SNP from first model in the model.

Joseph P. McElroy, et al. Hum Mol Genet. 2010 August 1;19(15):3080-3088.

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