We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Figure 1

Figure 1. From: Cognitive Effects of Nicotine: Genetic Moderators.

A cartoon illustrating the hypothesized effects of nicotine on the regulation of dopamine (DA), glutamate and acetylcholine (ACh) release in the prefrontal cortex (PFC), a region thought to be essential in mediating cognitive enhancement from nicotine. Nicotine enhances the release of glutamate and DA, which leads to increased Ach release and the potential activation of presynaptic glutamate and DA receptors on cholinergic terminals. The type and exact location of these receptors remains to be elucidated. See (Briand et al., 2007; Parikh et al., 2008; Sarter et al., 2009) for details.

Aryeh I. Herman, et al. Addict Biol. ;15(3):250-265.

Supplemental Content

Filter your results:

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Write to the Help Desk