Results: 2

1.
Fig. 2

Fig. 2. From: Identification of key genes for carcinogenic pathways associated with colorectal adenoma-to-carcinoma progression.

Comparison of protein expression levels for AURKA and PDGFRB in colorectal adenomas and CRCs. Immunohistochemical stainings for AURKA and PDGFRB confirmed overexpression of both proteins in CRCs compared to colorectal adenomas. AURKA staining can be found in the epithelial cells, while PDGFRB expression is observed in tumor stroma. Representative examples of AURKA and PDGFRB staining are shown for colorectal adenoma and carcinoma tissue. Digital images were obtained with a 20× objective (AURKA) and a 10× objective (PDGFRB)

Anke H. Sillars-Hardebol, et al. Tumour Biol. 2010 April;31(2):89-96.
2.
Fig. 1

Fig. 1. From: Identification of key genes for carcinogenic pathways associated with colorectal adenoma-to-carcinoma progression.

Comparison of mRNA expression levels for key genes of pathway activity in colorectal adenomas and CRCs. Boxplots showing mRNA expression levels of 37 colorectal adenomas and 31 colorectal adenocarcinomas, based on oligonucleotide microarray expression data. Expression of key genes was significantly higher in CRC compared to adenomas (p values < 1e-5). aAURKA; bPLK1; cADRM1; dSSSCA1; eSPARC; and fPDGFRB

Anke H. Sillars-Hardebol, et al. Tumour Biol. 2010 April;31(2):89-96.

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