Results: 3

1.
Figure 2

Figure 2. From: Population level impact of an imperfect prophylactic HSV-2 vaccine.

Impacts of adolescence and mass vaccine interventions in Kisumu, Kenya administered in 2010 using a vaccine with efficacies of VES =30%, VEP =75%, and VEI =0. (A) Time series of prevalence values. The source of population survey data is the Four-City study [9] (B) Time series of incidence rate values.

Ramzi A. Alsallaq, et al. Sex Transm Dis. ;37(5):290-297.
2.
Figure 3

Figure 3. From: Population level impact of an imperfect prophylactic HSV-2 vaccine.

Impact of mass vaccination in diverse HSV-2 settings having the same hierarchy of sexual risk as in Kisumu, Kenya. (A) Number of vaccination procedures needed per each HSV-2 infection averted at varying baseline HSV-2 prevalence levels before vaccine administration. (B) HSV-2 excess prevalence at endemic equilibrium (prevalence post-intervention subtracted from prevalence pre-intervention) at varying HSV-2 baseline prevalence levels. Vaccine properties are as in Figure 2.

Ramzi A. Alsallaq, et al. Sex Transm Dis. ;37(5):290-297.
3.
Figure 1

Figure 1. From: Population level impact of an imperfect prophylactic HSV-2 vaccine.

A set of mixed scenarios for the impact of HSV-2 vaccination. The vaccine utility (Φ), the vaccinee infection fitness (Ψ), and the basic reproduction number (R0V) for a scenario versus (A) vaccine efficacy of reducing susceptibility to HSV-2 (VES) at VEP =10% and VEI =0, (B) vaccine efficacy of reducing susceptibility to HSV-2 (VES) at VEP =75% and VEI =0, (C) vaccine efficacy of reducing shedding frequency (VEP) at VES =10% and VEI =0, (D) vaccine efficacy of reducing shedding frequency (VEP) at VES =30% and VEI =0, (E) vaccine efficacy of reducing infectivity (VEI) at VES =10% and VEP =10%, and (F) vaccine efficacy of reducing infectivity (VEI) at VES =30% and VEP =75%. In all these plots f =100% (fraction of adolescents vaccinated), r =10% (risk compensation), and the vaccine is assumed to have a lifelong immunity.

Ramzi A. Alsallaq, et al. Sex Transm Dis. ;37(5):290-297.

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