Results: 2

1.
Figure 1

Figure 1. From: Autologous and Allogeneic Cellular Therapies for High-Risk Pediatric Solid Tumors.

Kaplan–Meier curves showing OS and EFS for consecutively treated patients undergoing tandem autologous HSCT for high-risk neuroblastoma. The patients were conditioned with carboplatin/etoposide/cyclophosphamide for the first autologous HSCT procedure, followed by melphalan/TBI for the second. (a) OS from diagnosis, (b) EFS from diagnosis and (c) EFS from diagnosis stratified by MYCN (nMYC) amplification. Modified from Fish and Grupp, Bone Marrow Transplantation (2008) 41, 159–165.

David Barrett, et al. Pediatr Clin North Am. ;57(1):47-66.
2.
Figure 2

Figure 2. From: Autologous and Allogeneic Cellular Therapies for High-Risk Pediatric Solid Tumors.

Effect of TCA on peripheral blood CD4 cell recovery after immunoablative and myeloablative tandem HSCT for neuroblastoma. Patients were given autologous, costimulated, activated T cell infusions on the indicated day after the second HSCT. In 4 patients, an engraftment syndrome (Eng Synd) was observed, consisting of a pruritic rash with or without fever. This correlated with higher CD4 counts after TCA. Similar results were seen in the CD8 count (data not shown).

David Barrett, et al. Pediatr Clin North Am. ;57(1):47-66.

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