Results: 4

1.
Figure 4.

Figure 4. From: Metformin Supplementation and Life Span in Fischer-344 Rats.

Kaplan–Meier survival plots for CON, CR, MET, and PF–MET (CON: n = 31; CR: n = 40; MET; n = 40; and PF–MET: n = 40). Note: CON = control; CR = calorie restriction; MET = metformin; PF–MET = pair fed to metformin.

Daniel L. Smith, et al. J Gerontol A Biol Sci Med Sci. 2010 May;65A(5):468-474.
2.
Figure 3.

Figure 3. From: Metformin Supplementation and Life Span in Fischer-344 Rats.

Core body temperature (mean ± SD) at age 27, 39, 52, and 65 weeks (at 06:00 hours).

Daniel L. Smith, et al. J Gerontol A Biol Sci Med Sci. 2010 May;65A(5):468-474.
3.
Figure 1.

Figure 1. From: Metformin Supplementation and Life Span in Fischer-344 Rats.

Food intake and body weight. (A) Food intake (mean ± SD in grams/rat/week) for CON, CR, MET, and PF–MET groups recorded every 3–4 weeks following group randomization. (B) Body weight (mean ± SD in grams/rat) for CON, CR, MET, and PF–MET groups every 4 weeks following group randomization. Note: CON = control; CR = calorie restriction; MET = metformin; PF–MET = pair fed to metformin.

Daniel L. Smith, et al. J Gerontol A Biol Sci Med Sci. 2010 May;65A(5):468-474.
4.
Figure 2.

Figure 2. From: Metformin Supplementation and Life Span in Fischer-344 Rats.

Glucose and insulin response. (A) Glucose levels (milligrams per deciliter) obtained at 06:00 hours during the indicated week (age 27, 39, 52, and 65 weeks) for CON, CR, MET, and PF–MET (mean ± SD for all surviving rats). (B) Insulin levels (nanograms per milliliter) obtained at 06:00 hours during the indicated week (age 27, 39, 52, and 65 weeks; mean ± SD for 12 rats per study group). *p < .05. Note: CON = control; CR = calorie restriction; MET = metformin; PF–MET = pair fed to metformin.

Daniel L. Smith, et al. J Gerontol A Biol Sci Med Sci. 2010 May;65A(5):468-474.

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