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Results: 2

1.
Figure 1

Figure 1. From: Methods for Investigating Gene-Environment Interactions in Candidate Pathway and Genome-Wide Association Studies.

Conceptual basis for G×E interactions in bladder and colon cancer (33, 65, 71)

Duncan Thomas. Annu Rev Public Health. ;31:21-36.
2.
Figure 2

Figure 2. From: Methods for Investigating Gene-Environment Interactions in Candidate Pathway and Genome-Wide Association Studies.

Example of a four-way interaction among two environmental factors, well done red meat (R/M = rare-medium, WD = well done) and smoking, and two genes, CYP1A2 phenotype (L = ≤ median; H = > median) and NAT2 (S/I = slow-intermediate, R = rapid). Data from Table 6 of (65), risks scaled separately for ever and never smokers (baseline RR = 1.29 (95%CI 0.7–2.3)).

Duncan Thomas. Annu Rev Public Health. ;31:21-36.

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