Results: 2

1.
Figure 2

Figure 2. From: Differentially expressed alternatively spliced genes in Malignant Pleural Mesothelioma identified using massively parallel transcriptome sequencing.

Differential expression of specific exon junctions in MPM and normal lung samples. Average expression levels of exon junctions in ACTG2 (A) and CDK4 (B) differ statistically significantly between MPM and normal lung samples. Individual expression levels of exon junctions in ACTG2 (C) and CDK4 (D) can be used to classify MPM and normal tissue samples using the median value as a cut-off. Error bars, SEM. Arrows indicate misclassified samples.

Lingsheng Dong, et al. BMC Med Genet. 2009;10:149-149.
2.
Figure 1

Figure 1. From: Differentially expressed alternatively spliced genes in Malignant Pleural Mesothelioma identified using massively parallel transcriptome sequencing.

Identification of alternatively spliced transcripts using second generation sequencing data. The 454 sequencing reads that span exon junctions provide information about alternatively spliced variants in the human transcriptome. For example, two typical alternatively spliced variants ('a' and 'b') of a single gene are shown in the top half of the figure. The lower half of the figure shows how different 454 reads may align to cDNA sequences generated from the mRNA providing evidence of alternatively splicing events.

Lingsheng Dong, et al. BMC Med Genet. 2009;10:149-149.

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