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Results: 4

1.
Figure 3

Figure 3. From: In vivo Tumor Grading of Prostate Cancer using Quantitative 111In-Capromab Pendetide SPECT/CT.

Reconstructed uniform phantom image in transaxial view. The phantom was in cylindrical shape, and aqueous solution of 111InCl3 was mixed with water, and filled in the cylindrical volume partially to ensure a complete mixing with water. The line profile shows a fairly uniform intensity pattern except small dips near the edge close to the wall.

Youngho Seo, et al. J Nucl Med. ;51(1):31.
2.
Figure 2

Figure 2. From: In vivo Tumor Grading of Prostate Cancer using Quantitative 111In-Capromab Pendetide SPECT/CT.

Correlation plots of AUVs against Gleason tumor grades from 10 patient data. All patients went through preoperative SPECT/CT imaging of 111In-capromab pendetide and prostatectomies. Gleason tumor grades were obtained from anatomical pathology of the prostatectomies. AUVs were calculated before and after the deconvolution-based PVE correction was applied.

Youngho Seo, et al. J Nucl Med. ;51(1):31.
3.
Figure 1

Figure 1. From: In vivo Tumor Grading of Prostate Cancer using Quantitative 111In-Capromab Pendetide SPECT/CT.

The effect of deconvolution-based partial volume error correction on reconstructed SPECT/CT images. (A) and (C) are before correction (left column) and (B) and (D) are after the PVE correction. The transaxial (top row) and coronal (bottom row) views are shown. White arrows indicate areas of the uptake patterns (the prostate gland), showing improved spatial resolution after the PVE correction.

Youngho Seo, et al. J Nucl Med. ;51(1):31.
4.
Figure 4

Figure 4. From: In vivo Tumor Grading of Prostate Cancer using Quantitative 111In-Capromab Pendetide SPECT/CT.

Recovery coefficients were measured using a modified NEMA/IEC body phantom that contains multiple prostate lesions (7.77 ml the smallest) and bladder lesion (146 ml). (A) A photograph of the modified NEMA/IEC body phantom. (B) The chart that compares recovery coefficients in reconstructed images with and without PVE correction. The deconvolution-corrected measurement recovers tracer concentrations significantly even in a very small volume (7.77 ml), while the deconvolution correction effect is less significant in a large lesion (146 ml). Reconstructed phantom image slices (transaxial view showing the two filled lesions) uncorrected (C) and corrected (D) by the PVE correction algorithm are also shown.

Youngho Seo, et al. J Nucl Med. ;51(1):31.

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