Figure 1

Figure 1. From: Vitamin D and Non-Hodgkin Lymphoma Risk in Adults: A Review.

Proposed mechanism. It is hypothesized that extra-renal conversion of 25(OH)D to the active vitamin D metabolite (1,25(OH)2D) results in autocrine and paracrine signaling to control lymphocyte cell proliferation and decrease lymphoma risk.

Jennifer L. Kelly, et al. Cancer Invest. ;27(9):942-951.

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