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Fig. 1

Fig. 1. From: Hydroxocobalamin dose escalation improves metabolic control in cblC.

Metabolite levels obtained during OHCbl dose escalation. Baseline levels correspond to the OHCbl dose of 1 mg 3×/week. (a) Dose-dependent reduction of plasma MMA and tHcy and increase in methionine levels. Normal levels: MMA<0.27 μmol/L; tHcy 0–13 μmol/L and methionine 7–47 μmol/L. (b) Table of relevant metabolite concentrations in plasma

N. Carrillo-Carrasco, et al. J Inherit Metab Dis. 2009 December;32(6):728-731.

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