Results: 2

1.
Figure 2

Figure 2. From: Determining the Etiology of Pulmonary Edema by the Edema Fluid-to-Plasma Protein Ratio.

Percent of patients alive and breathing without assistance during the first 28 days after enrollment. Panel A shows the entire cohort (n = 390). P = 0.058 for group with EF/PL < 0.65 compared to group with EF/PL ≥ 0.65 by Cox proportional hazards regression analysis. Panel B is restricted to the subgroup (n = 200) in whom the edema fluid was sampled within 3 hours of endotracheal intubation. P = 0.005 for group with EF/PL < 0.65 compared to compared to group with EF/PL ≥ 0.65 by Cox proportional hazards regression analysis.

Lorraine B. Ware, et al. Eur Respir J. ;35(2):331.
2.
Figure 1

Figure 1. From: Determining the Etiology of Pulmonary Edema by the Edema Fluid-to-Plasma Protein Ratio.

Receiver operator curve (ROC) analyses of the utility of the Edema Fluid to Plasma Protein Ratio (EF/PL) for differentiating the etiology of acute pulmonary edema. A. Comparison of the EF/PL ratio to the clinical diagnosis based on all information available at the end of the hospitalization, excluding patients with a clinical diagnosis of a mixed etiology of acute pulmonary edema (n = 356). The EF/PL ratio determined early in the hospital course had excellent diagnostic discrimination for ALI vs. CPE with an area under the curve (AUC) of 0.84 (95% CI 0.79 to 0.88). B. The same analysis was restricted to the subgroup of patients who had pulmonary edema fluid sampled within 3 hours of endotracheal intubation (n = 183). In this group, the diagnostic performance of the EF/PL ratio was similar with an AUC of 0.85 (95% CI 0.79 to 0.91). C and D. For these analyses, the patients with a clinical diagnosis of a mixed etiology of acute pulmonary edema were classified as having ALI, and the entire cohort (n = 390, panel C) and the subgroup with pulmonary edema fluid sample within 3 hours of endotracheal intubation (n = 200, panel D) were analyzed. For the entire cohort, the AUC was 0.81 (95% CI 0.77 to 0.86). For the subgroup with edema fluid sampled within 3 hours of endotracheal intubation the AUC was 0.81 (95% CI 0.74 to 0.87).

Lorraine B. Ware, et al. Eur Respir J. ;35(2):331.

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