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Results: 3

1.
Fig. 2

Fig. 2. From: A GENE EXPRESSION MODEL OF INTRINSIC TUMOR RADIOSENSITIVITY: PREDICTION OF RESPONSE AND PROGNOSIS AFTER CHEMORADIATION.

Receiver-operating characteristic curve using predicted radiosensitivity index (RSI) for radiosensitivity predictions. Using a threshold RSI of 0.4619592, the predictor has an 80% sensitivity and 82% specificity, with positive predictive value (PPV) of 86%. The estimated area under the curve (AUC) is 0.84.

Steven A. Eschrich, et al. Int J Radiat Oncol Biol Phys. ;75(2):489-496.
2.
Fig. 1

Fig. 1. From: A GENE EXPRESSION MODEL OF INTRINSIC TUMOR RADIOSENSITIVITY: PREDICTION OF RESPONSE AND PROGNOSIS AFTER CHEMORADIATION.

Radiosensitivity index (RSI) is correlated with clinical response to concurrent radiochemotherapy in rectal and esophageal cancer patients. (A) The mean predicted RSI of responders is significantly lower than in nonresponders in both clinical cohorts (esophageal: p = 0.05, rectal: p = 0.03). (B) Predicted RSI of each individual patient in the cohorts (combined: p = 0.001511).

Steven A. Eschrich, et al. Int J Radiat Oncol Biol Phys. ;75(2):489-496.
3.
Fig. 3

Fig. 3. From: A GENE EXPRESSION MODEL OF INTRINSIC TUMOR RADIOSENSITIVITY: PREDICTION OF RESPONSE AND PROGNOSIS AFTER CHEMORADIATION.

Radiosensitivity index (RSI) distinguishes clinical populations with different disease-related outcomes in a head-and-neck cancer (HNC) cohort of 92 patients treated with definitive concurrent radiochemotherapy. Using the 25th percentile (RSI < 0.023), there is a superior 2-year locoregional control (LRC) in the predicted radiosensitive group (86% vs. 61%, p = 0.05).

Steven A. Eschrich, et al. Int J Radiat Oncol Biol Phys. ;75(2):489-496.

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