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Fig. 1

Fig. 1. From: Systemic mastocytosis associated with t(8;21)(q22;q22) acute myeloid leukemia.

a Pretreatment bone marrow aspirate (case 3) showing predominantly myeloblasts admixed with rare mast cells. Note the hypergranular cytoplasm within the mast cells (Wright-Giemsa, ×500). b Day 14 post-treatment bone marrow aspirate (case 3) with prominent mast cell infiltrate (Wright-Giemsa, ×200). c Immunohistochemistry for tryptase (case 3) highlights the mast cell infiltrate (×200). d Mast cells show expression of CD25 (case 3), a characteristic feature of neoplastic mast cells (×200)

Sheeja T. Pullarkat, et al. J Hematop. 2009 March;2(1):27-33.

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