Results: 4

1.
Fig. 2.

Fig. 2. From: Spinal nociceptin mediates electroacupuncture-related modulation of visceral sympathoexcitatory reflex responses in rats.

Influence of opioid antagonism on nociceptin response. A: effect of electroacupuncture (EA) on reflex blood pressure responses. B: blood pressure responses to intrathecal injection of nociceptin receptor antagonist after onset of EA. Labels a–d on the bars correspond to the tracings shown above the bars. C: blood pressure responses to intrathecal injection of both nociceptin and opioid receptor antagonist during EA. *P < 0.05, significant difference compared with pre-EA. N, number of animals.

Wei Zhou, et al. Am J Physiol Heart Circ Physiol. 2009 August;297(2):H859-H865.
2.
Fig. 4.

Fig. 4. From: Spinal nociceptin mediates electroacupuncture-related modulation of visceral sympathoexcitatory reflex responses in rats.

Spinal neural pathway of nociceptin in EA modulation. Microinjection of nociceptin/orphanin FQ peptide antagonist in the dorsal horn (DH; A) or the intermediolateral column (IML; B) at T1 following 20 min of EA. *P < 0.05. Bars represent pressor responses to gastric distension. C: composite map displaying sites of microinjections in the DH and the IML. N, number of animals.

Wei Zhou, et al. Am J Physiol Heart Circ Physiol. 2009 August;297(2):H859-H865.
3.
Fig. 3.

Fig. 3. From: Spinal nociceptin mediates electroacupuncture-related modulation of visceral sympathoexcitatory reflex responses in rats.

Spinal nociceptin system in cardiovascular responses to electrical stimulation in the rostral ventrolateral medulla (rVLM). A: effect of intrathecal injection of nociceptin on the BP responses to electrical stimulation of the rVLM (bars). *P < 0.05, significant difference after intrathecal injection of nociceptin. B: composite map displaying sites of insertion of stimulation electrode (*) in the rVLM. All insertions were unilateral (side chosen randomly). Sections are 2.0–2.5 and 2.5–3.0 mm caudal to the interaural line (Ref. 33). Py, pyramidal tract; Amb, ambiguous nucleus; 7, facial nucleus; Sp5, spinal trigeminal nucleus; ION, inferior olivary nucleus; N, number of animals.

Wei Zhou, et al. Am J Physiol Heart Circ Physiol. 2009 August;297(2):H859-H865.
4.
Fig. 1.

Fig. 1. From: Spinal nociceptin mediates electroacupuncture-related modulation of visceral sympathoexcitatory reflex responses in rats.

Gastric distension response to nociceptin in the spinal cord. A: blood pressure tracings of an individual animal, represented by a, b, and c, are displayed above representative bar histograms. Small arrows on tracings indicate time of gastric distension. B: effect of nociceptin injected intrathecally at T1–2 (long arrow) on mean arterial pressure (MAP) responses to gastric distension. C: effect of naloxone and nociceptin/orphanin FQ peptide receptor antagonist on nociceptin-induced attenuation of pressor responses induced by gastric distension. Baseline blood pressures (in mmHg) before distension are indicated below each bar. Gastric distension was repeated every 10 min. Bars show increase in MAP (±SE) induced by distension of the stomach. *P < 0.05, significant difference after intrathecal injection of nociceptin. N, number of animals.

Wei Zhou, et al. Am J Physiol Heart Circ Physiol. 2009 August;297(2):H859-H865.

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