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Figure 1

Figure 1. From: The Consequences of HIV Infection and Antiretroviral Therapy Use For Cardiovascular Disease Risk: Shifting Paradigms.

Multiple factors contribute to CVD risk among patients with HIV infection, including traditional risk factors as well as mechanisms related to viral replication and ART. While ART use may decrease HIV-mediated CVD risk via suppression of viral replication, it is also associated with drug toxicity that itself is known to confer CVD risk. There may also be other HIV- and ART-specific CVD risk factors not discussed here (dotted lines). Thus, the net influence of ART on CVD risk, in the setting of HIV infection, remains to be defined.

Jason V. Baker, et al. Curr Opin HIV AIDS. ;4(3):176-182.

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