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Results: 5

1.
Figure 2

Figure 2. From: HODGKIN LYMPHOMA: AN UPDATE ON ITS BIOLOGY WITH NEWER INSIGHTS INTO CLASSIFICATION.

Lymphocyte depleted CHL with abundant HRS-cells in a background rich in histiocytes, but with few lymphocytes (H&E).

Haresh Mani, et al. Clin Lymphoma Myeloma. ;9(3):206-216.
2.
Figure 3

Figure 3. From: HODGKIN LYMPHOMA: AN UPDATE ON ITS BIOLOGY WITH NEWER INSIGHTS INTO CLASSIFICATION.

Lymphocyte rich CHL with HRS cells within expanded follicles, mainly at the periphery in the mantle and marginal zone (CD15 immunostain).

Haresh Mani, et al. Clin Lymphoma Myeloma. ;9(3):206-216.
3.
Figure 4

Figure 4. From: HODGKIN LYMPHOMA: AN UPDATE ON ITS BIOLOGY WITH NEWER INSIGHTS INTO CLASSIFICATION.

In nodular lymphocyte predominant HL, LP cells are strongly positive for CD20 and are seen in the context of lymphoid follicles (CD20 immunostain).

Haresh Mani, et al. Clin Lymphoma Myeloma. ;9(3):206-216.
4.
Figure 1

Figure 1. From: HODGKIN LYMPHOMA: AN UPDATE ON ITS BIOLOGY WITH NEWER INSIGHTS INTO CLASSIFICATION.

Nodular sclerosis Hodgkin lymphoma is characterized by broad bands of birefringent collagen. Lacunar variants of HRS cells often cluster within the nodules (H&E).

Haresh Mani, et al. Clin Lymphoma Myeloma. ;9(3):206-216.
5.

Figure 5. From: HODGKIN LYMPHOMA: AN UPDATE ON ITS BIOLOGY WITH NEWER INSIGHTS INTO CLASSIFICATION.

A. The classical RS cell is binucleate, each nucleus contains a prominent eosinophilic nucleolus with perinucleolar halos giving the cell an “owl-eye” appearance (H&E). B. The LP cell, the neoplastic cell in NLPHL, has a multilobate/folded nucleus with smaller basophilic nucleoli giving the cell a “popcorn” appearance (H&E).

Haresh Mani, et al. Clin Lymphoma Myeloma. ;9(3):206-216.

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