Results: 2

1.
Figure 1

Figure 1. From: Common mechanisms of PIKK regulation.

Diagram of PIKK domain structures showing the locations of the kinase, FAT, and FATC domains.

Courtney A. Lovejoy, et al. DNA Repair (Amst). ;8(9):1004-1008.
2.
Figure 2

Figure 2. From: Common mechanisms of PIKK regulation.

Common themes of PIKK regulation. Each PIKK is regulated through localization (to a nucleic acid or intracellular compartment), a partner protein that is required for both the recruitment and activation of the kinase, and a protein or protein/nucleic acid activator.

Courtney A. Lovejoy, et al. DNA Repair (Amst). ;8(9):1004-1008.

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