Figure 1.

Figure 1. From: Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.

Association of different rs16969968-rs588765 diplotypes with CHRNA5 mRNA expression (global test P < 0.0001). Diplotype analysis confirms that rs588765 alters CHRNA5 mRNA expression (GG_CC versus GG_TT; P = 3.66 × 10−5). It also demonstrates that rs16969968 does not influence CHRNA5 mRNA expression. The bars represent mean ± SD of CHRNA5 mRNA expression. We used SAS software to run t-test for pair-wise comparison of CHRNA5 mRNA expression with the specific genotype combination. The comparison of three diplotype groups (GGCC, AGCC and AACC) was analyzed with F-test.

Jen C. Wang, et al. Hum Mol Genet. 2009 August 15;18(16):3125-3135.

Supplemental Content

Filter your results:

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Write to the Help Desk