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Results: 4

1.
Figure 1

Figure 1. Cumulative risk of spontaneous preterm birth in relation to duration of preconceptional folate supplementation.. From: Preconceptional Folate Supplementation and the Risk of Spontaneous Preterm Birth: A Cohort Study.

Folate = 0*, no preconceptional folate supplementation; Folate <1 yr*, preconceptional folate supplementation for less than a year; Folate > = 1 yr*, preconceptional folate supplementation for a year or longer. *Test for trend of survivor functions, p = 0.01.

Radek Bukowski, et al. PLoS Med. 2009 May;6(5):e1000061.
2.
Figure 2

Figure 2. Risk of spontaneous preterm birth before 32 wk in relation to duration of preconceptional folate supplementation.. From: Preconceptional Folate Supplementation and the Risk of Spontaneous Preterm Birth: A Cohort Study.

Proportion (mean ± standard error) of spontaneous preterm births before 32 wk in women with no preconceptional folate supplementation and supplementation for <1, 1–2, 3–4, 5–6, 7–11, and >12 mo.

Radek Bukowski, et al. PLoS Med. 2009 May;6(5):e1000061.
3.
Figure 3

Figure 3. Relative risk of spontaneous preterm birth in relation to duration of preconceptional folate supplementation.. From: Preconceptional Folate Supplementation and the Risk of Spontaneous Preterm Birth: A Cohort Study.

HRs and 95% CIs for spontaneous preterm birth in women with preconceptional folate supplementation for a year or longer (•) or less than a year (▪), compared to women without preconceptional folate supplementation – reference value (○), from Cox proportional hazard regression. *Wald test for equality of hazard ratios, testing the joint hypothesis that coefficients are equal to 0 and that they are equal to each other [66]. SPTB, spontaneous preterm birth.

Radek Bukowski, et al. PLoS Med. 2009 May;6(5):e1000061.
4.
Figure 4

Figure 4. Stratified analysis of association between preconceptional folate supplementation ≥1 y and the risk of spontaneous preterm birth before 32 wk.. From: Preconceptional Folate Supplementation and the Risk of Spontaneous Preterm Birth: A Cohort Study.

ORs and 95% CIs of spontaneous preterm birth before 32 wk for preconceptional folate supplementation for ≥1 y, stratified for a given characteristic and adjusted for all other maternal characteristics. p-Values are estimated for interaction terms between duration of folate supplementation and given characteristic. The OR for BMI <18.5 could not be estimated, as there were no cases of spontaneous preterm birth before 32 wk among women using folate supplementation for ≥1 y and with BMI <18.5. MA, maternal age; Educ, completed years of education; PARA No PPTB, parous woman without a history of prior preterm birth; PARA PPTB, parous woman with a history of prior preterm birth.

Radek Bukowski, et al. PLoS Med. 2009 May;6(5):e1000061.

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