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Results: 4

1.
Figure 1

Figure 1. From: Structure/Activity Relationship Studies of Small-Molecule Inhibitors of Wnt Response.

The structures of IWR-1 (1) and IWR-2 (2).

Jianming Lu, et al. Bioorg Med Chem Lett. ;19(14):3825-3827.
2.
Figure 2

Figure 2. From: Structure/Activity Relationship Studies of Small-Molecule Inhibitors of Wnt Response.

The structural deviation of 5052 from 1 and their dose-response curves.

Jianming Lu, et al. Bioorg Med Chem Lett. ;19(14):3825-3827.
3.
Figure 3

Figure 3. From: Structure/Activity Relationship Studies of Small-Molecule Inhibitors of Wnt Response.

Inhibition of fin regeneration in zebrafish by IWR’s. Arrows indicate the points of resection.

Jianming Lu, et al. Bioorg Med Chem Lett. ;19(14):3825-3827.
4.
Figure 4

Figure 4. From: Structure/Activity Relationship Studies of Small-Molecule Inhibitors of Wnt Response.

The murine whole blood metabolism experiments of 1.

Jianming Lu, et al. Bioorg Med Chem Lett. ;19(14):3825-3827.

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