Results: 4

1.
Figure 2

Figure 2. Genetic risk score and risk for type 2 diabetes. From: Joint Effects of Common Genetic Variants on the Risk for Type 2 Diabetes in U.S. Men and Women of European Ancestry.

Results are based on the count genetic risk score for pooled data from men and women. Adjusted for age (quintiles), sex, and body mass index (quintiles).

Marilyn C. Cornelis, et al. Ann Intern Med. 2009 April 21;150(8):541-550.
2.
Figure 1

Figure 1. Association of reported loci and risk for type 2 diabetes in pooled analysis of men and women. From: Joint Effects of Common Genetic Variants on the Risk for Type 2 Diabetes in U.S. Men and Women of European Ancestry.

Odds ratios (95% CIs) are adjusted for age (quintiles), sex, and body mass index (quintiles). SNP = single nucleotide polymorphism.

Marilyn C. Cornelis, et al. Ann Intern Med. 2009 April 21;150(8):541-550.
3.
Figure 4

Figure 4. Receiver-operating characteristic curves for type 2 diabetes. From: Joint Effects of Common Genetic Variants on the Risk for Type 2 Diabetes in U.S. Men and Women of European Ancestry.

The curves are based on logistic regression models incorporating conventional risk factors (age, sex, body mass index, family history of diabetes, smoking, alcohol intake, and physical activity) with and without the count GRS. AUC = area under the curve; GRS = genetic risk score.

Marilyn C. Cornelis, et al. Ann Intern Med. 2009 April 21;150(8):541-550.
4.
Figure 3

Figure 3. Joint effects of conventional risk factors and genetic risk score on risk for type 2 diabetes. From: Joint Effects of Common Genetic Variants on the Risk for Type 2 Diabetes in U.S. Men and Women of European Ancestry.

Values on bars indicate sample size. Top. Joint effects of body mass index and count genetic risk score (adjusted for age and sex) for pooled data from men and women. Bottom. Joint effects of family history of diabetes and count genetic risk score (adjusted for age, sex, and body mass index) for pooled data from men and women.

Marilyn C. Cornelis, et al. Ann Intern Med. 2009 April 21;150(8):541-550.

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