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1.
Figure 2

Figure 2. From: Caveolae, Ion Channels and Cardiac Arrhythmias.

Schematic of CAV3 mutations associated with cardiac phenotype genetic diseases. Shown are locations of Cav-3 mutations identified in of Long QT syndrome type 9 (LQT9; red), sudden infant death syndrome (SIDS; pink) and hypertrophic cardiomyopathy (orange) patients. Mutation T78M in the membrane insertion region of the Cav3 was found to be associated with cases of both LQT9 and SIDS.

Ravi C. Balijepalli, et al. Prog Biophys Mol Biol. ;98(2-3):149-160.
2.
Figure 1

Figure 1. From: Caveolae, Ion Channels and Cardiac Arrhythmias.

Electron microscopic images of adult mouse ventricular tissue. Panel A, immunogold staining of caveolin-1. Staining for caveolin-1 is observed only in the caveolae (arrows) of endothelial cell. In contrast the ventricular myocyte caveolae (arrow heads) had no specific caveolin-1 staining (SL, sarcolemma; Z, z line of the myofibril). Panel B, immunogold co-localization of the Cav1.2 subunit of L-type Ca2+ channel and caveolin-3. Cav1.2 (large gold particles) and caveolin-3 (small gold particle) are co-localized relative to myocyte caveolae (arrow heads) in sarcolemma (SL) and not in the endothelial caveolae (arrows). Cav1.2 staining is also noticed in the T-tubules (Tt), where Cav3 staining is absent. Scale bar, 100 nm.

Ravi C. Balijepalli, et al. Prog Biophys Mol Biol. ;98(2-3):149-160.

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