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Figure 1

Figure 1. From: Association of TTR polymorphisms with hippocampal atrophy in Alzheimer disease families.

Locations and linkage disequilibrium (LD) map structure of single nucleotide polymorphisms (SNPs) in the TTR gene region. The LD maps for the African American (AA) and Caucasian family samples are shown above and below the gene structure diagram, respectively. Measures of LD among all possible pairs of SNPs (identified by number using the scheme in Table 1) are shown graphically according to the shade of red where white represents very low Dā€™ and dark red represents very high Dā€™ and numerically denoted by the r2 values within each square. Indeterminate estimates of LD are denoted by blue shading. The TTR gene structure including intergenic regions (white), introns (green) and exons (purple) is shown starting from the 5ā€™ upstream region on the left.

Karen T. Cuenco, et al. Neurobiol Aging. ;32(2):249-256.

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