Results: 2

1.
Figure 1

Figure 1. From: Folic Acid and Risk of Prostate Cancer: Results From a Randomized Clinical Trial.

Design of the trial and flow of participants.

Jane C. Figueiredo, et al. J Natl Cancer Inst. 2009 March 18;101(6):432-435.
2.
Figure 2

Figure 2. From: Folic Acid and Risk of Prostate Cancer: Results From a Randomized Clinical Trial.

Kaplan–Meier plot of the prostate cancer–free status over time among the 643 men randomized to placebo and folic acid treatment in this study. The 95% confidence intervals (CIs) for probability of remaining free of cancer are shown at 3, 6, and 9 years for both treatment groups. The numbers of patients at risk for prostate cancer at 3, 6, and 9 years were 284, 274, and 10, respectively, in the placebo group and 300, 233, and 10 in the folic acid group. *Cox proportional hazard models were used to obtain hazard ratios (HRs) and 95% confidence intervals and Wald tests to obtain P values. In the figure, hazard ratio is age adjusted. The multiadjusted hazard ratio (with adjustment for aspirin treatment group, alcohol use, baseline multivitamin use and plasma levels of vitamins B2, B6, and B12) was 2.58 (95% CI = 1.14–5.86, P = 0.02).

Jane C. Figueiredo, et al. J Natl Cancer Inst. 2009 March 18;101(6):432-435.

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