Results: 4

1.
Figure 1

Figure 1. From: Beta Amyloid in Alzheimer's Disease: Increased Deposition in Brain Is Reflected in Reduced Concentration in Cerebrospinal Fluid.

Linear regression analysis between [11C]PiB cerebrum/vermis uptake ratio and CSF Aβ42. Standardized regression coefficient Beta = −0,478; p = .01. Aβ42, beta amyloid [1-42]; [11C]PiB, carbon-11-labeled Pittsburgh Compound B; CSF, cerebrospinal fluid.

Timo Grimmer, et al. Biol Psychiatry. ;65(11):927-934.
2.
Figure 4

Figure 4. From: Beta Amyloid in Alzheimer's Disease: Increased Deposition in Brain Is Reflected in Reduced Concentration in Cerebrospinal Fluid.

Partial volume effect corrected voxel-based regression analysis between [11C]PiB uptake and CSF Aβ42. Significant (p < .01) associations projected to the surface. Aβ42, beta amyloid [1-42]; [11C]PiB, carbon-11-labeled Pittsburgh Compound B; CSF, cerebrospinal fluid; L, left; R, right.

Timo Grimmer, et al. Biol Psychiatry. ;65(11):927-934.
3.
Figure 2

Figure 2. From: Beta Amyloid in Alzheimer's Disease: Increased Deposition in Brain Is Reflected in Reduced Concentration in Cerebrospinal Fluid.

Correlation analyses between [11C]PiB cerebrum/vermis uptake ratios and CSF Aβ42 in anatomically defined regions of interest. Correlation coefficients (Pearson): (A) r = −.503, p = .005; (B) r = −.400, p = .029; (C) r = −.460, p = .011. Aβ42, beta amyloid [1-42]; [11C]PiB, carbon-11-labeled Pittsburgh Compound B; CSF, cerebrospinal fluid.

Timo Grimmer, et al. Biol Psychiatry. ;65(11):927-934.
4.
Figure 3

Figure 3. From: Beta Amyloid in Alzheimer's Disease: Increased Deposition in Brain Is Reflected in Reduced Concentration in Cerebrospinal Fluid.

Voxel-based regression analysis between [11C]PiB uptake and CSF Aβ42. Significant (p < .01) associations: (A) projected to the surface; (B–D) overlaid on T2-scans (average of 152 scans, implemented in SPM2). (B) axial, (C) coronal, (D) saggital. Aβ42, beta amyloid [1-42]; [11C]PiB, carbon-11-labeled Pittsburgh Compound B; CSF, cerebrospinal fluid; L, left; R, right; x/y/z, coordinates of slices in Talairach space.

Timo Grimmer, et al. Biol Psychiatry. ;65(11):927-934.

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