Figure 1

Figure 1. From: ANTIOXIDANT THERAPEUTIC ADVANCES IN COPD.

Inflammatory response is mediated by inhaled and/or cellular oxidants. These oxidants activate alveolar macrophages, neutrophils, eosinophils, and epithelial cells, leading to ROS/RNS generation, redox imbalance, and activation of redox-sensitive transcription factors. They may act as signaling mediators and further involve in the inflammatory responses in patients with COPD. Antioxidants inhibit the oxidative stress by induction of GSH biosynthesis and change of redox status. It is possible that therapeutic administration of antioxidants will be effective in the treatment of COPD. ROS: reactive oxygen species; RNS: reactive nitrogen species

Irfan Rahman. Ther Adv Respir Dis. ;2(6):351-374.

Supplemental Content

Filter your results:

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Write to the Help Desk