Figure 1

Figure 1. From: Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?.

Proposed model for the regulatory roles played by Hsp90 in AD progression. Hsp90 can promote AD by facilitating the activities of protein kinases that cause the pathological features of AD. LTP, long-term potentiation; CTF, carboxyl-terminal fragment – cleavage product of APP (amyloid precursor protein); MT, microtubule.

Wenjie Luo, et al. BMC Neurosci. 2008;9(Suppl 2):S7-S7.

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