Fig. 1. From: A Genome-Wide Association Study of Schizophrenia Using Brain Activation as a Quantitative Phenotype.

Regions of the Genome Showing Evidence of Association in the Quantitative Trait (QT) analysis. Physical map of the single-nucleotide polymorphisms (SNPs) associated with (a) ROBO2-ROBO1 region, (b) TNIK gene, and (c) CTXN3-SLC12A2 region produced by WGAViewer. The topmost sector is the ideogram of chromosomes 3 or 5; the vertical red line shows the relative of location of gene region. Below this is the graph showing the –log P significance values of the individual SNPs on the imaging phenotype (dorsolateral prefrontal cortex) for the right hemisphere. The small blue lines below this indicate the location of the exons in the transcripts annotated (translated region of the DNA). The vertical lines above the accompanying triangular matrix indicate the SNP locations and demonstrate the LD pattern between SNPs (D') calculated using Haploview 4·1. The warmer colors on the flame scale indicate greater LD, while the blue indicates absence of LD.

Steven G. Potkin, et al. Schizophr Bull. 2009 January;35(1):96-108.

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