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Results: 3

1.
Fig. 3

Fig. 3. From: Chronic administration of antipsychotics impede behavioral recovery after experimental traumatic brain injury.

Mean (± S.E.M.) swim speed (cm/sec). A significant decrease in swim speed was observed in the TBI + RISP (0.45 mg/kg and 4.5 mg/kg), TBI + HAL, Sham + RISP, and Sham + HAL groups vs. the TBI + VEH group [*p < 0.05]. All groups, except the TBI + VEH, swam significantly slower than the Sham + VEH group [**p < 0.05]. Lastly, the Sham + HAL group was significantly slower than the TBI + RISP (0.045 mg/kg) group [^p < 0.05].

Anthony E. Kline, et al. Neurosci Lett. ;448(3):263-267.
2.
Fig. 1

Fig. 1. From: Chronic administration of antipsychotics impede behavioral recovery after experimental traumatic brain injury.

Mean (± S.E.M.) time (sec) to traverse a narrow beam prior to, and after, TBI or Sham injury. RISP (all doses) and HAL hindered the ability to recover TBI-induced motor deficits vs. VEH [*p < 0.05]. All TBI and both the Sham + RISP and Sham + HAL groups were significantly impaired vs. the Sham + VEH group [**p < 0.05].

Anthony E. Kline, et al. Neurosci Lett. ;448(3):263-267.
3.
Fig. 2

Fig. 2. From: Chronic administration of antipsychotics impede behavioral recovery after experimental traumatic brain injury.

Mean (± S.E.M.) time (sec) to locate either a hidden (submerged) or visible (raised) platform in a water maze. RISP (all doses) and HAL hindered the ability to acquire spatial learning relative to VEH [*p < 0.05]. All TBI and both the Sham + RISP and Sham + HAL groups were significantly impaired vs. the Sham + VEH group [**p < 0.05]. The TBI + RISP (4.5 mg/kg) group also exhibited visible platform deficits vs. the TBI + VEH group [p = 0.0002].

Anthony E. Kline, et al. Neurosci Lett. ;448(3):263-267.

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