Results: 3

1.
Figure 2

Figure 2. From: Polyoma virus infection and urothelial carcinoma of the bladder following renal transplantation.

Renal biopsy 2 years post-transplantation from patient 7, showing a minor non-specific inflammatory cell infiltrate on H&E (A). Immunohistochemistry for PV T-Ag (B) shows staining of tubular epithelial cell nuclei, confirming a diagnosis of PVN.

I S D Roberts, et al. Br J Cancer. 2008 November 4;99(9):1383-1386.
2.
Figure 3

Figure 3. From: Polyoma virus infection and urothelial carcinoma of the bladder following renal transplantation.

Urine cytology in patient 8 initially suggested BKV infection (A) but a sample 3 months later was more in keeping with urothelial carcinoma (B), confirmed as carcinoma in situ on biopsy (C).

I S D Roberts, et al. Br J Cancer. 2008 November 4;99(9):1383-1386.
3.
Figure 1

Figure 1. From: Polyoma virus infection and urothelial carcinoma of the bladder following renal transplantation.

Tumour tissue from patient 7, showing high-grade invasive urothelial carcinoma (A), with focal squamous differentiation (B). High power (C) reveals no evidence of typical viral inclusions on H&E stain. Immunohistochemistry for PV T-Ag is negative in non-neoplastic urothelium adjacent to the tumour (D), but shows intense nuclear staining in almost all tumour cells (E and F).

I S D Roberts, et al. Br J Cancer. 2008 November 4;99(9):1383-1386.

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