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Results: 2

1.
Fig. 1

Fig. 1. From: Incorporating ethnicity into genetic risk assessment for Alzheimer disease: the REVEAL study experience.

Cumulative risk estimates to age 85 for Alzheimer disease (AD) for first-degree relatives of AD patients based on APOE genotype, gender, and ethnicity. □ White females; African American females; white males; and ■ African American males.

Kurt D. Christensen, et al. Genet Med. ;10(3):207-214.
2.
Fig. 2

Fig. 2. From: Incorporating ethnicity into genetic risk assessment for Alzheimer disease: the REVEAL study experience.

Sample cumulative risk curves presented to study participants all of whom have a first-degree relative with Alzheimer disease (AD). The risk curves apply to participants who are found to have an APOE 3/4 genotype. “APOE 34” refers to the participants' individual risk profiles specific to their genotype–gender–ethnicity combinations. “First Degree” is a comparison line that shows the risk for AD among the population of people with the same gender–ethnicity combination as the participant and a first-degree relative with AD. “General Population” is another comparison line that shows the risk for AD within the same ethnic group as the participant regardless of gender or whether a person has an affected first-degree relative. Explanations of each line are provided verbally to study participants.

Kurt D. Christensen, et al. Genet Med. ;10(3):207-214.

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