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1.
Fig. 1.

Fig. 1. From: Distinct genomic signatures of adaptation in pre- and postnatal environments during human evolution.

Experimental design. (A) Phylogenetic tree showing the taxa sampled in the present study. Open circle indicates the LCA of rodents and primates. HAS lineages are indicated in color: yellow, primate stem lineage; blue, ape stem lineage; magenta, human terminal lineage. Dashed lines indicate rodent lineages. A gene was retained on the HAS list if it showed dN/dS >1 on any HAS lineage(s) and dN/dS <1 on all rodent-specific lineages. (B) Tissues analyzed in the present study. (Left) Postnatal tissues. (Right) Prenatal tissues.

Monica Uddin, et al. Proc Natl Acad Sci U S A. 2008 March 4;105(9):3215-3220.
2.
Fig. 2.

Fig. 2. From: Distinct genomic signatures of adaptation in pre- and postnatal environments during human evolution.

Proportion of adaptive signatures on each HAS branch, by tissue and cluster. The top three FACs are represented, with cluster one appearing as the outermost ring. Yellow, proportion of adaptive signatures occurring on the primate stem lineage; blue, proportion of adaptive signatures occurring on the ape stem lineage; magenta, proportion of adaptive signatures occurring on the human terminal lineage. (A) Fetal brain. (B) Adult whole brain. (C) Fetal liver. (D) Adult liver. (E) Fetal lung. (F) Adult lung. (G) Fetal thyroid. (H) Adult thyroid. (I) Placenta. (J) Adult uterus. Only among fetal tissues (A, C, E, G, I) and the adult uterus do 50% or more adaptive events occur on the human terminal in at least one of the top three FACs.

Monica Uddin, et al. Proc Natl Acad Sci U S A. 2008 March 4;105(9):3215-3220.

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