Figure 1

Figure 1. From: Residual Prostate Cancer Following Radiotherapy: A Study of Radical Cystoprostatectomy Specimens.

Histologic appearance of irradiated prostate with and without active CaP at the time of RCP. Panel A demonstrates benign glands with radiation effect. The represented specimen was treated with EBRT for low risk CaP. RCP was performed 48 months following RT for recurrent pTis of the bladder. Panel B demonstrates active CaP at the time of RCP following EBRT. Gleason pattern 3 CaP is apparent within the previously irradiated prostate. The patient presented with intermediate risk CaP with a PSA of 14.9 ng/ml and Gleason 3+3=6 on transrectal biopsy. Following RT the patient did not demonstrate biochemical recurrence with a PSA nadir of 0.3 ng/ml. RCP was performed 106 months following RT for invasive urothelial carcinoma.

David J. Kaplan, et al. Urology. ;72(3):654-658.

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