Results: 3

1.
Figure 1

Figure 1. From: Differential Interleukin-10 Production Stratified by -571 Promoter Polymorphism in Purified Human Immune Cells.

Differential IL-10 production from monocytes containing the -571 C-to-A promoter polymorphism. Monocytes were enriched from peripheral blood using magnetic bead affinity purification and cultured for 24 hrs in the presence or absence of LPS (10 μg/ml). Supernatants were collected and IL-10 levels measured, separated according to IL-10 genotype: homozygous CC (n=11) and AA (n=6). P<0.05 is considered statistically significant.

John W. Steinke, et al. Cell Immunol. ;249(2):101-107.
2.
Figure 2

Figure 2. From: Differential Interleukin-10 Production Stratified by -571 Promoter Polymorphism in Purified Human Immune Cells.

IL-10 production from T cells containing the -571 C-to-A promoter polymorphism differs depending on stimuli in a genotype-specific manner. T cells were enriched from peripheral blood using magnetic bead affinity purification and cultured for 24 hrs in the presence or absence of PMA/ionomycin (0.1 μg/ml), Con A (10 μg/ml) or anti-CD3/anti-CD28 (1 μg/ml). Supernatants were collected and IL-10 levels measured, separated according to IL-10 genotype: homozygous CC (n=11) and AA (n=6). P<0.05 is considered statistically significant.

John W. Steinke, et al. Cell Immunol. ;249(2):101-107.
3.
Figure 3

Figure 3. From: Differential Interleukin-10 Production Stratified by -571 Promoter Polymorphism in Purified Human Immune Cells.

B cells display differential IL-10 production on promoters containing the -571 C-to-A polymorphism in response to diverse stimuli. B cells were enriched from peripheral blood using magnetic bead affinity purification and cultured for 24 hrs in the presence or absence of LPS (10 μg/ml) or anti-IgM (10 μg/ml). Supernatants were collected and IL-10 levels measured, separated according to IL-10 genotype: homozygous CC (n=11) and AA (n=6). P<0.05 is considered statistically significant.

John W. Steinke, et al. Cell Immunol. ;249(2):101-107.

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Write to the Help Desk