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Results: 5

1.
Figure 4

Figure 4. From: Increased Hemodynamic Response in the Hippocampus, Thalamus and Prefrontal Cortex During Abnormal Sensory Gating in Schizophrenia.

P50 sensory gating ratios in schizophrenia subjects (N=11) and healthy comparison subjects (N=11).

Jason R. Tregellas, et al. Schizophr Res. ;92(1-3):262-272.
2.
Figure 5

Figure 5. From: Increased Hemodynamic Response in the Hippocampus, Thalamus and Prefrontal Cortex During Abnormal Sensory Gating in Schizophrenia.

Correlations between P50 sensory gating ratios and hemodynamic response during fMRI sensory gating task in the thalamus, hippocampus and DLPFC.

Jason R. Tregellas, et al. Schizophr Res. ;92(1-3):262-272.
3.
Figure 1

Figure 1. From: Increased Hemodynamic Response in the Hippocampus, Thalamus and Prefrontal Cortex During Abnormal Sensory Gating in Schizophrenia.

Schematic representation of experimental design. For all conditions, two seconds of scanning was followed by 6 s of silence for inhibitory circuitry to resent. Following the silent period, subjects were presented with a single click, repeated clicks each separated by 500ms, or silence.

Jason R. Tregellas, et al. Schizophr Res. ;92(1-3):262-272.
4.
Figure 3

Figure 3. From: Increased Hemodynamic Response in the Hippocampus, Thalamus and Prefrontal Cortex During Abnormal Sensory Gating in Schizophrenia.

Activation across groups of bilateral primary auditory cortex in response to single click (N=24). Statistical parametric maps thresholded at P < 0.01, overlaid onto the average T1-weighted anatomy of all subjects. Local maxima located at x = -42, y = -33, z = -12 (left Heschl's gyrus), x = 42, y = -30, z = 12 (right Heschle's gryus)

Jason R. Tregellas, et al. Schizophr Res. ;92(1-3):262-272.
5.
Figure 2

Figure 2. From: Increased Hemodynamic Response in the Hippocampus, Thalamus and Prefrontal Cortex During Abnormal Sensory Gating in Schizophrenia.

Increased hemodynamic response in subjects with schizophrenia (N=12) relative to healthy comparison subjects (N=12) during sensory gating. Statistical parametric maps thresholded at P < 0.01, overlaid onto the average T1-weighted anatomy of all subjects. Local maxima located at x = -24, y = -18, z = -15 (left hippocampus), x = -9, y = -12, z = 3 (left thalamus), x = 9, y = -21, z = 3 (right thalamus), x = -48, y = 36, z = 27 (left DLPFC). Graphs below show mean blood oxygenation level dependent (BOLD) responses in terms of % signal change, relative to the global mean, for the sensory gating measure, (repeated clicks – single click), and for each condition separately, compared to silence. Error bars indicate standard deviations.

Jason R. Tregellas, et al. Schizophr Res. ;92(1-3):262-272.

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