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Fig. 1.

Fig. 1. From: Childhood maltreatment predicts adult inflammation in a life-course study.

The association of childhood maltreatment with biomarkers of inflammation. (A) Mean (and SE) of logged hsCRP according to maltreatment experiences. In an ordinary least-squares regression model adjusted for sex and antiinflammatory drug use, definite maltreatment (b = 0.35, SE = 0.13, t = 2.58; P = 0.01), but not probable maltreatment (b = 0.09, SE = 0.09, t = 1.07; P = 0.29), predicted an increase in logged hsCRP levels. (B) Mean (and SE) of fibrinogen according to maltreatment experiences. Definite maltreatment (b = 0.15, SE = 0.07, t = 2.20; P = 0.03), but not probable maltreatment (b = 0.06, SE = 0.04, t = 1.39; P = 0.17), predicted an increase in fibrinogen levels. (C) Mean (and SE) of WBC count according to maltreatment experiences. Both probable maltreatment (b = 0.55, SE = 0.14, t = 3.95; P < 0.001) and definite maltreatment (b = 0.67, SE = 0.21, t = 3.18; P = 0.002) predicted an increase in WBC count. (D) Mean (and SE) of a factor score for inflammation according to maltreatment experiences. The inflammation factor has a standardized mean of 0 and SD of 1. Both probable maltreatment (b = 0.19, SE = 0.08, t = 2.44; P = 0.02) and definite maltreatment (b = 0.39, SE = 0.12, t = 3.36; P = 0.001) predicted an increase in the factor score for inflammation.

Andrea Danese, et al. Proc Natl Acad Sci U S A. 2007 January 23;104(4):1319-1324.

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