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Results: 3

1.
<b>Figure 3.</b>

Figure 3.. From: African Americans with Asthma.

LD plots and tagging SNPs from a selected segment on chromosome 12q for two populations. Illustration of SNPs selected by the Tagger algorithm (90) on a set of 20 SNPs at r2 = 0.8. A represents the LD between 20 SNPs and European Americans from Tangier Island, Virginia (estimated from 354 chromosomes), and B represents the same set of SNPs in founders from the African-Caribbean population from Barbados (estimated 900 chromosomes). SNPs retained by Tagger are shown with blue marker identifiers for the two populations and include 12 of 20 SNPs for the Tangier sample and 18 of 20 (80%) SNPs for the Barbados sample.

Kathleen C. Barnes, et al. Proc Am Thorac Soc. 2007 January;4(1):58-68.
2.
<b>Figure 2.</b>

Figure 2.. From: African Americans with Asthma.

Number of published genetic association studies on asthma and associated phenotypes in different ethnic populations (European/European American, African descent, Hispanic, Asian, other) during 1987–2005. Summaries are derived from the data provided in the online supplement by Ober and Hoffjan (12), which include summaries of associations between specific variants in 120 HLA and non-HLA genes, phenotype, and the population studied, and are based on a compilation of 492 references. In studies that included more than one independent population, each population was counted. “African descent” includes African-American and African-Caribbean populations, and populations from continental Africa (Tunisia, South Africa). “Hispanic” includes Puerto Rican, Mexican American, Costa Rican, Mexican, and Venezuelan. “Other” includes ethnically mixed populations, and aboriginal Australian, Indonesian, and Hawaiian populations.

Kathleen C. Barnes, et al. Proc Am Thorac Soc. 2007 January;4(1):58-68.
3.
<b>Figure 1.</b>

Figure 1.. From: African Americans with Asthma.

Comparison of pairwise linkage disequilibrium (LD) estimates (D′) in three populations. Pairwise LD estimated between each of 20 single nucleotide polymorphism (SNP) markers genotyped on chromosome 12q (67953342−68500427; [National Center for Biotechnology Information (NCBI) build 35; Illumina panel 42 (Illumina, Inc., San Diego, CA)] using Haploview (Julian Maller, developer, Massachusetts Institute of Technology). Haplotype blocks are shown according to the definition by Gabriel and colleagues (45). A represents the LD between 20 single nucleotide polymorphisms (SNPs) and founders from the Yoruban (YRI) population published by the HapMap project (www.hapmap.org; estimated from 120 chromosomes); B shows the same set of SNPs in an African-Caribbean population from Barbados (estimated from 900 chromosomes); and C shows the same set of SNPs in European Americans from Tangier Island, Virginia (estimated from 354 chromosomes). The 20 SNPs are aligned to the pairwise LD plot. Squares illustrate strong (red), little/no (white), and nonsignificant (blue) LD.

Kathleen C. Barnes, et al. Proc Am Thorac Soc. 2007 January;4(1):58-68.

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