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1.
Figure 2

Figure 2. From: The Vpr protein from HIV-1: distinct roles along the viral life cycle.

Three-dimensional structure of the HIV-1 Vpr protein (from [15]). The three α-helices (17–33, 38–50, 55–77) are colored in pink, blue and orange, respectively; the loops and flexible domains are in green. We can the Trp54 residue localized between the second and the third a-helix, and that is likely accessible for protein-protein interaction with UNG2 [54].

Erwann Le Rouzic, et al. Retrovirology. 2005;2:11-11.
2.
Figure 1

Figure 1. From: The Vpr protein from HIV-1: distinct roles along the viral life cycle.

Schematic view of the early steps of the HIV-1 infection of a target cell. The functional events in which the Vpr protein is involved are highlighted. Vpr has been shown to play multiple functions during the virus life cycle, including an effect on the accuracy of the reverse-transcription process, the nuclear import of the viral DNA as a component of the pre-integration complex, cell cycle progression, regulation of apoptosis, and the transactivation of the HIV-LTR as well as host cell genes.

Erwann Le Rouzic, et al. Retrovirology. 2005;2:11-11.

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