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Results: 5

1.
Figure 2

Figure 2. From: Dissociation in human prefrontal cortex of affective influences on working memory-related activity.

Mean normalized magnitude of startle blink (n = 9) evoked during the delay period after the presentation of cues in the DET and WM tasks. (Standard error bars are shown.)

William M. Perlstein, et al. Proc Natl Acad Sci U S A. 2002 February 5;99(3):1736-1741.
2.
Figure 5

Figure 5. From: Dissociation in human prefrontal cortex of affective influences on working memory-related activity.

Task- and valence-related effects on behavioral performance in 23 subjects who performed a modified version of the task wherein probe stimuli contained only two rather than nine pictures.

William M. Perlstein, et al. Proc Natl Acad Sci U S A. 2002 February 5;99(3):1736-1741.
3.
Figure 4

Figure 4. From: Dissociation in human prefrontal cortex of affective influences on working memory-related activity.

Mean range-corrected (xi − minimum/maximum − minimum) signal intensity as a function of pleasant and unpleasant valence for the right dorsolateral and orbitofrontal regions in the WM task. Nine of ten subjects showed the inverse DLPFC-OFC valence pattern.

William M. Perlstein, et al. Proc Natl Acad Sci U S A. 2002 February 5;99(3):1736-1741.
4.
Figure 1

Figure 1. From: Dissociation in human prefrontal cortex of affective influences on working memory-related activity.

Cognitive tasks, sample stimuli, and fMRI scanning sequence. (a) Stimuli (70% cues, 30% probes) were presented for 2.5 s followed by an 11.5-s delay. Pleasant, neutral, and unpleasant pictures were presented randomly within each trial block. Subjects indicated if an infrequently presented probe matrix contained the immediately preceding cue (WM) or an image in the surround that was identical to the image in the center (DET). (b) fMRI acquisition was synchronized to stimulus onset, and four 3.5-s scans were acquired during the course of each 14-s trial.

William M. Perlstein, et al. Proc Natl Acad Sci U S A. 2002 February 5;99(3):1736-1741.
5.
Figure 3

Figure 3. From: Dissociation in human prefrontal cortex of affective influences on working memory-related activity.

Task- and valence-related effects on prefrontal cortex activity (n = 10). (a) Slice image illustrates regions of the right DPFC (BA 46/9) and medial OFC (BA 10/11) that exhibited significant task-related changes in signal intensity (P < .0025; white, memory > detection; black, detection > memory). Maximum z values for dorsolateral and medial frontal clusters were 4.61 and 4.01, respectively; cluster sizes were 95 and 102 voxels, respectively. Numbers in parentheses show the standard reporting coordinates (ref. 40; x, y, z) for voxels exhibiting the most significant P value. R, right; L, left. (b) Task-related signal intensity change as a function of scan-in-trial shown as the percentage change in signal intensity from scan 1 in the DET task. (c) Mean range-corrected (xi − minimum/maximum − minimum) signal intensity as a function of task and valence for the right dorsolateral (left) and medial orbitofrontal (right) clusters. Signal intensity was averaged across all significant voxels in each cluster. (Standard error bars are shown.)

William M. Perlstein, et al. Proc Natl Acad Sci U S A. 2002 February 5;99(3):1736-1741.

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