Results: 2

1.
Figure  1

Figure 1. From: A Second Locus for an Axonal Form of Autosomal Recessive Charcot-Marie-Tooth Disease Maps to Chromosome 19q13.3.

Pedigree and haplotype analysis of markers from chromosome 19q13 in members of family CR-1, from Costa Rica, with ARCMT2B. Haplotypes segregating with the disease are given in black. Although the exact genealogical connection is not shown, because of the complexity of the family structure, branches A, B, and C have common ancestors. Healthy members of the families, not used for linkage analysis, are summarized to the right of the nuclear families, showing the number of individuals in each case.

Alejandro Leal, et al. Am J Hum Genet. 2001 January;68(1):269-274.
2.
Figure  2

Figure 2. From: A Second Locus for an Axonal Form of Autosomal Recessive Charcot-Marie-Tooth Disease Maps to Chromosome 19q13.3.

Critical region of ARCMT2B on chromosome 19q13.3. Key recombinations are shown in individuals C-3.1 and A-5.1, defining the ARCMT2B interval identified in the Costa Rican family. The gene that causes this form of CMT is located in a 5.5-cM region between D19S902 and D19S907. The linkage map of markers from chromosome 19 and genetic distances (in centimorgans) are assigned based on information from the Généthon human linkage map. Blackened regions in chromosomal representations indicate haplotypes related to the disease, and unblackened regions indicate haplotypes not related to the disease.

Alejandro Leal, et al. Am J Hum Genet. 2001 January;68(1):269-274.

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